MICROBIOME FOODS
Proven Research Benefits of Our Ingredients
MICROBIOME FOOD INCREASES HEALTHY GUT BACTERIA
Research studies consistently show that consumption of fermented oats, alfalfa, barley, and wheat can increase populations of beneficial gut bacteria (probiotics) such as Lactobacilli and Bifidobacterium, along with the production of beneficial short-chain fatty acids (SCFAs).
Reviews nutritional aspects and prebiotic potential of fermented cereal-based products, suggesting certain cereal components like β-glucans and arabinoxylans are selectively utilized by host microorganisms, which contributes to a healthy gut microbiome.
Fermented Foods, Health and the Gut Microbiome - PMC 2021
NATIONAL INSTITUTE OF HEALTH
By Natasha K Leeuwendaal 1, Catherine Stanton 1,2, Paul W O’Toole 2,3, Tom P Beresford 1,*
Highlights that fermented foods lead to increases in beneficial gut bacteria, detailing a human study where fermented oat-based products significantly increased fecal Bifidobacterium and total bacterial counts.
Fermented Foods, Health and the Gut Microbiome - MDPI
by Natasha K. Leeuwendaal, Catherine Stanton, Paul W. O’Toole and Tom P. Beresford
April, 2022
Discusses how fermented oat-based products can increase beneficial gut bacteria like Bifidobacterium and reduce total cholesterol in humans.
Fermented Minor Grain Foods: Classification, Functional ...
PMC Home (.gov)
Reviews the probiotic potential of fermented minor grains like oats, barley, and wheat, discussing how components, particularly polyphenols, support beneficial gut microbiota growth and that specific LAB strains are found in fermented oats.
Studies on Fermented Oats and Gut Bacteria
Fermented oats increase Bifidobacterium and Lactobacillus in healthy adults, enhancing gut health and immune response.
Regulatory Effect of Fermented Oat on Immune Cytokines and Gut ...
SciOpen
· 4 months ago
Fermented Barley
Study/Finding: Extracts of barley fermented with Lactobacillus plantarum JDM1 (LFBE) significantly increased the proportion of Bifidobacterium and reduced inflammation in high-fat diet-induced obese rats.
Journal: PubMed (Journal of Applied Microbiology)
Study/Finding: A fermented barley found to increase levels of Lactobacilli and Bacteroides (bacteria with anti-inflammatory properties) in a mouse model of colitis, offering protective roles against inflammatory bowel disease.
Journal: BMC Complementary Medicine and Therapies
Study/Finding: Feeding weaner pigs diets with fermented barley (vs. unfermented) enhanced gut health by positively modulating the immune response and gut bacterial composition.
Journal: ScienceDirect (Journal of Animal Science and Biotechnology)
Fermented/Whole Alfalfa
Studies on alfalfa have primarily been conducted in animal models (pigs, yaks), showing positive effects on gut microbiota composition, often linked to its high fiber content.
Study/Finding: Supplementation with alfalfa meal or fermented alfalfa meal in pig diets increased the abundance of beneficial bacteria (including Prevotella and fibrinolytic bacteria) and reduced potential pathogens like Streptococcus suis.
Journal: Frontiers in Veterinary Science
Highlights how fermented oats can increase Bifidobacterium and Lactobacillus in healthy adults' guts, also modulating immune-inflammatory factors and enhancing defecation.
Fermented Oats as a Novel Functional Food - PMC - PubMed Central
PMC Home (.gov)
· 2 years ago
Reviews fermented oats, detailing their production, prebiotic effects promoting probiotic bacteria growth, and health benefits like blood sugar regulation and weight management, but excludes alfalfa, barley, or wheat.
Here are specific research studies and the journals in which they were found:
Fermented/Whole Oats
Study/Finding: Oat intake, both whole and fermented, is consistently associated with significant increases in beneficial bacterial groups, particularly Lactobacilli and Bifidobacterium spp., in human and in vitro studies.
Journal: The Journal of Nutrition
Study/Finding: A randomized, controlled human trial found that oat consumption significantly increased Lactobacillus levels and positively impacted the gut microbiome, suggesting a prebiotic effect that contributes to cholesterol reduction.
Journal: Frontiers in Immunology
Study/Finding: An in vitro fermentation model found that whole oat bran (rather than isolated components) had a specific "bifidogenic" effect, promoting the growth of Bifidobacterium.
Journal: The British Journal of Nutrition
Study/Finding: Fermentation with GRAS (Generally Recognized as Safe) microorganisms, such as certain Lactobacilli and Bifidobacteria strains, promotes the growth of these beneficial microbes within the oat matrix itself.
Journal: ScienceDirect (Journal not specified in snippet, likely Food Science related)
Study/Finding: Fermented alfalfa meal improved intestinal morphology and increased acetate concentration (an SCFA) in the colon of pigs, indicating enhanced microbial fermentation ability.
Journal: Frontiers in Microbiology
Study/Finding: Combining oat hay and alfalfa hay in yak calf diets changed gut microorganism composition, with the combination improving nutrient absorption and immune function.
Journal: MDPI (Molecules or Animals)
Reviews nutritional aspects and prebiotic potential of fermented cereal-based products, suggesting certain cereal components like β-glucans and arabinoxylans are selectively utilized by host microorganisms, which contributes to a healthy gut microbiome.
Fermented Foods, Health and the Gut Microbiome - PMC
PMC Home (.gov)
· 4 years ago
Highlights that fermented foods lead to increases in beneficial gut bacteria, detailing a human study where fermented oat-based products significantly increased fecal Bifidobacterium and total bacterial counts.
Fermented Foods, Health and the Gut Microbiome
MDPI
Discusses how fermented oat-based products containing an EPS-producing Pediococcusdamnosus strain can increase beneficial gut bacteria like Bifidobacterium and reduce total cholesterol in humans.
Fermented Minor Grain Foods: Classification, Functional ...
PMC Home (.gov)
Reviews the probiotic potential of fermented minor grains like oats, barley, and wheat, discussing how components, particularly polyphenols, support beneficial gut microbiota growth and that specific LAB strains are found in fermented oats.
Studies on Fermented Oats and Gut Bacteria
Fermented oats increase Bifidobacterium and Lactobacillus in healthy adults, enhancing gut health and immune response.
Regulatory Effect of Fermented Oat on Immune Cytokines and Gut ...
SciOpen
· 4 months ago
Highlights how fermented oats can increase Bifidobacterium and Lactobacillus in healthy adults' guts, also modulating immune-inflammatory factors and enhancing defecation.
Fermented Oats as a Novel Functional Food - PMC - PubMed Central
PMC Home (.gov)
· 2 years ago
Reviews fermented oats, detailing their production, prebiotic effects promoting probiotic bacteria growth, and health benefits like blood sugar regulation and weight management, but excludes alfalfa, barley, or wheat.
Relationship between Oat Consumption, Gut Microbiota Modulation ...
PMC Home (.gov)
· 2 years ago
Details how oat consumption can increase beneficial gut microbes (Bifidobacterium, Akkermansiamuciniphila, Lactobacillus, Roseburia, Faecalibacteriumprausnitzii), and reduce harmful ones (Enterobacteriaceae, Sutterellaceae).
Chlorella
Clinical trials and studies show Chlorella may help detoxify heavy metals (like lead, cadmium, dioxins) by binding to them and promoting excretion, and it also shows promise in reducing liver inflammation (NAFLD), lowering cholesterol, and potentially detoxifying food-borne carcinogens, with research often using Chlorella vulgaris in patients with existing metal exposure or liver issues, but more large-scale human trials are needed for definitive proof, particularly for general use.
Key Clinical Trial References & Findings
Heavy Metals (Lead, Cadmium, Dioxins):
< Yamaguchi et al. (2025)< : Found Chlorella effectively detoxified mycotoxins (molds) deoxynivalenol, ochratoxin A, fumonisin B1) in vivo (in living organisms) and in vivo (in test tube or outside of living organisms).
< Kim et al. (2003b) & Morita et al. (1999)< (Animal Studies): Showed Chlorellaintake helped eliminatetoxic metals like cadmium and dioxins in rats.
< Miyazaki et al. (2019)< (Human Study): A 90-day study with Chlorella in patients with dental amalgam fillings showed reduced levels of mercury, lead, and cadmium compared to baseline, indicating potential for detoxification in individuals exposed to these toxic metals.
Non-Alcoholic Fatty Liver Disease (NAFLD)< & Liver Enzymes:
< Panahi et al. (2015) & J. Yuh et al.: Showed Chlorella supplementation significantly reduced blood liver enzymes (AST, ALT) and weight in NAFLD Non Alcoholic Fatty Liver Disease patients, likely linked to weight loss. Note: over 60% of adults have NAFLD.
< A meta-analysis (2021)< : Confirmed Chlorella significantly lowered AST blood levels in NAFLD patients, supporting liver benefits.
< A meta-analysis (2020)< : Found Chlorella significantly lowered LDL ("bad") cholesterol and triglycerides in mildly hypercholesterolemic subjects, possibly by inhibiting lipid absorption.
Food-borne Carcinogens< (Heterocyclic Amines):
< Shim et al. (2009) & Other Studies (2015)< : Showed Chlorella helped reduce urinary levels of certain carcinogenic compounds (like MeIQx) in young adults exposed to cooked meat, suggesting detoxification of these cancer causing agents.
Immune Support (Indirect Detox):
< A randomized controlled trial (2005)< : Demonstrated a Chlorella-improved immune response to the influenza vaccine, potentially helping the body clear viral infections (another form of "detox").
In Summary: Research indicates Chlorella's potential to bind and remove toxins, improve liver health, and reduce cholesterol, with many studies focusing on specific patient groups (e.g., heavy metal exposure, NAFLD). While promising, more extensive human trials are needed to establish clear dosage and broad efficacy for general detoxification.